Polynucleotides Treatment - Skinology Medical Aesthetics Clinic - London UK - 1

Polynucleotides

Polynucleotide treatment can be beneficial in smoothing out fine lines and wrinkles, improving dark circles and under eye puffiness, enhancing skin hydration, reducing the appearance of scarring (including acne scarring), improving skin laxity, and restoring tone and elasticity of ageing or damaged skin. They can also help with hyperpigmentation, melasma and rosacea.

About Polynucleotides

Polynucleotides are naturally occurring molecules, made of chains of nucleotides which are the essential building blocks of DNA and RNA. They are derived from the sperm of salmon or trout and once extracted, they undergo a rigorous process of purification and sterilisation for medical use. When injected, polynucleotides deeply penetrate the skin, helping rejuvenation by improving hydration, promoting skin cell turnover and repair, and boosting skin quality.
Polynucleotides work by stimulating the production of collagen and elastin, the cells essential for maintaining skin firmness and elasticity. Polynucleotides improve deep skin hydration, resulting in the skin looking more plump, dewy and youthful. They also have anti-inflammatory and wound healing properties which help to reduce swelling, irritation, redness and other signs of skin damage.
Polynucleotides are most commonly used on the face but can also be injected to treat the neck, hands, arms and abdomen. They are particularly useful for managing delicate areas of the face, or where other treatments may not be appropriate, for example, under the eyes.
Results can last for 6-12 months depending on skin type, age and lifestyle factors. Regular maintenance treatments every 6-12 months are recommended for sustained results.
The treatment involves 3 steps. Your practitioner will support and guide you every step of the way.

Step 1: Consultation and Consent

A comprehensive consultation is always undertaken to assess your suitability for treatment, understand expectations and to help formulate a customised and safe plan should you decide to go ahead with treatment.

During the consultation, you will have the opportunity to discuss any specific skin concerns you may have. The practitioner will undertake a medical history and skin assessment and ask details about your current skincare routine. Based on the assessment, the practitioner will discuss whether you are suitable for polynucleotide treatment. If so, they will advise on a treatment plan and provide their expert opinion about realistic and expected outcomes. They will also discuss the possible side effects, any risks and the procedure in detail to allow you to make an informed choice about whether you wish to have the treatment.

You are strongly encouraged to consider all the benefits and risks explained to you as part of the consultation and clarify anything you are unsure about. It is important not to rush into any decisions. Treatment will only go ahead if both you and the practitioner agree and are happy to proceed, and after you have provided written consent to treatment.

You may be asked to stop using specific skincare products ahead of your treatment to optimise the results. Your practitioner will explain this during your consultation. One week before your appointment, you should avoid taking aspirin, ibuprofen, vitamin E, St John’s Wort and fish oil supplements as these can increase your risk of bleeding. You can however take paracetamol should you require pain relief. If you are taking prescribed medication, including aspirin, do not stop taking this without consulting with the practitioner or your GP beforehand.

You should avoid drinking any alcohol 24 hours before any polynucleotides treatment as this can also increase the risk of bleeding.

Step 2: Polynucleotide Treatment

The procedure will involve removing any make-up/skin care products from the treatment area. Thereafter, a topical anaesthetic cream will be applied and left on the skin for around 20-30 minutes to numb the skin and ease comfort. Once the skin is sufficiently numb, the anaesthetic cream will be gently wiped off and the skin will be thoroughly cleansed with an antiseptic. The practitioner will then mark up the treatment area before injecting the polynucleotide using a needle and/or cannula (a blunt flexible tube). You may feel some discomfort or stinging as the product is injected. You are likely to have small bumps, resembling bee stings and pin-pricks of blood at the injection sites. This will reduce within a few hours. Depending on the skin concern and area being treated, the treatment can take from 30-60 minutes.

Pre- and post-treatment photos will be taken and held by the clinic for medical documentation purposes.

Aftercare is an extremely important part of the treatment to minimise risk and ensure good results are achieved. Detailed aftercare advice will be provided at your consultation but will include using fresh towels and pillowcases. Not touching or rubbing the face; keeping the area clean and make-up free; and avoiding alcohol, strenuous exercise/gym, saunas, steam rooms, excessive sun exposure or extremes of heat or cold for 24-48 hours. No scrubbing the skin or using active skin products such as salicylic acid, retinoids for 48 hours.

Step 3: Review

  • A free review will be offered following your treatment to check your process and recovery.

At a Glance

  • Procedure time: 30-60 minutes
  • Anaesthetic: Topical anaesthetic is applied
  • Duration of results: 6 months
  • Treatment recovery time: Immediate
  • Expected side effects: These include, but are not limited to some localised redness, bleeding, stinging, tenderness and mild swelling during or post-treatment. These usually resolve quickly. Polynucleotides are derived from trout or salmon and therefore they are not suitable for anyone allergic to fish. Bruising, infection and allergic reactions are possible but rare side effects.
  • Back to work: Same day

Book An Appointment

Whether you’re exploring skincare treatments, anti-ageing solutions, or advanced aesthetic procedures, we’re here to help you look and feel your best. Book your personalised consultation with our expert team at Skinology Medical Aesthetics clinics at any of our three locations in London.

Skin Concerns & Treatment Options

Common Skin Concerns & Treatment Options Wrinkle Relaxing Dermal Fillers Chemical Peels Microneedling Mesotherapy Polynucleotides Profhilo® / Skin Boosters Medical Grade Skin Care
Lines and wrinkles
Facial volume loss
Jowls
Laughter lines
Neck lines
Nasolabial folds
Smokers lines
Downturned smile
Gummy smile
Double chin
Thin lips
Saggy / lax skin
Aged skin
Age spots
Hyperpigmentation
Melasma
Acne
Acne Scars
Poor texture / dull skin
Hollow eyes / dark circles
LEADERSHIP TO EXCELLENCE

Founder & Clinical Director

Yogita Dawda

As the Founder and Clinical Director of Skinology Medical Aesthetics, my passion for dermatology started during university as an undergraduate and stemmed from my personal struggle with acne throughout my teens and early adulthood. I recall vividly the effect of having bad skin on my confidence but with the right support, I was able to love my skin and myself again.

After graduating in 1999, I started working in a large NHS teaching hospital where I was fortunate to gain experience in a wide range of clinical areas. In 2002, I chose to specialise in mental health where I practised as an independent prescribing pharmacist. In 2022, I became one of the first credentialed Consultant Pharmacists by the Royal Pharmaceutical Society (RPS), awarded to individuals who have demonstrated delivery of expert level clinical care and influenced positive change across the healthcare.

Testimonials

Redefining Beauty, One Story at a Time.
5/5

I was very nervous to get lip filler but Yogita made the whole experience very comfortable and I’m delighted with the outcome.

5/5

My skin became dull and lifeless during the menopause. Skinology personalised an easy and affordable skincare plan that’s made my skin feel rejuvenated.

5/5

I had 3 sessions of microneedling which really helped improve my acne scars.

Ageless Elegance

GRACEFUL SKIN AT EVERY AGE.
Mesotherapy Treatment - Skinology Medical Aesthetics Clinic - London UK - 4

FAQs

A Medical Aesthetics Clinic is run or led by medical professionals who use their medical expertise to provide non-surgical cosmetic treatments to enhance or maintain one’s natural beauty and help address specific concerns such as wrinkles, pigmentation, acne, scars and ageing. All procedures are performed by qualified medical professionals.

Like most other medical treatments, non-surgical cosmetic procedures carry some risks so it’s important to ensure the procedure is performed by a professional qualified and experienced in medical aesthetics with appropriate knowledge in facial anatomy and expertise in recognising and managing any complications safely should they occur.

Absolutely. At Skinology Medical Aesthetics, before any treatment is provided, a face to face consultation with a medical practitioner is essential to help us understand your concerns, undertake a thorough assessment and recommend the most suitable treatment plan tailored to your needs and budget.

You can book an appointment through our website. Alternatively, you can email or call us directly.